Elevated blood C-reactive protein (CRP) levels are strongly associated with cardiovascular disease (CVD) and atherogenesis. Japanese researchers conducted a cross-sectional survey of 971 Japanese men and women using food frequency questionnaires to determine whether an association exists between fish consumption and CRP levels. The results of their analysis suggest that higher intakes of the omega-3 fatty acids EPA and DHA from fish are independtly related to a lower prevalence of CRP elevations in the Japanese population.
"Dietary long-chain n-3 fatty acids of marine origin and serum C-reactive protein concentrations are associated in a population with a diet rich in marine products." Am J Clin Nutr. 2006;84:223-9.