Vitamin E supplementation was found to significantly reduce the risk of life-threatening blood clots in the veins (thromboembolisms).
According to the American Heart Association: “Over 200,000 new cases of Venous Thromboembolism occur annually. Of these, 30 percent die within 30 days, one-fifth suffer sudden death due to Pulmonary Embolisms (blood clots in the lungs), and about 30 percent develop recurrent clots within 10 years.”
In the Women's Health Study, 39,876 participants over 45 years of age received either 600 IU per day of vitamin E or a placebo (fake capsule) every other day for 10 years. Researchers found that women who took vitamin E had a 21% decrease in risk of developing blood clots as opposed to women not taking the vitamin E supplement. In women who had a history of blood clots, the reduction in risk while supplementing with vitamin E jumped to 44%, and in women with a genetic mutation that increased their risks of developing blood clots, vitamin E supplementation resulted in a 49% reduction in risk!
Glynn, R. et al., “Effects of Random Allocation to Vitamin E Supplementation on the Occurrence of Venous Thromboembolism: Report From the Women's Health Study”. Circulation 2007;116;1497-1503.